PolyMAC

One-Step PolyMAC for homogeneous enrichment of phosphopeptides
prior to mass spectrometry analysis

PolyMAC is based on a metal-ion functionalized soluble nanopolymer to chelate phosphopeptides in a homogeneous aqueous environment. Compared to current strategies based on solid phase micro- and nano-particles, PolyMAC demonstrates outstanding reproducibility, exceptional selectivity, fast chelation times, and high phosphopeptide recovery from complex mixtures.

Due to low stoichiometry of phosphorylation, phosphopeptide enrichment is a critical step for successful phosphoproteomics experiments. Available here is a novel chemical strategy termed Polymer-based Metal-ion Affinity Capture (PolyMAC) for the isolation of phosphopeptides with exceptionally high reproducibility, selectivity, and sensitivity.

One-Step PolyMAC for homogeneous enrichment of phosphopeptides prior to mass spectrometry analysis

PolyMAC is based on a metal-ion functionalized soluble nanopolymer to chelate phosphopeptides in a homogeneous aqueous environment. Compared to current strategies based on solid phase micro- and nano-particles, PolyMAC demonstrates outstanding reproducibility, exceptional selectivity, fast chelation times, and high phosphopeptide recovery from complex mixtures.

Due to low stoichiometry of phosphorylation, phosphopeptide enrichment is a critical step for successful phosphoproteomics experiments. Available here is a novel chemical strategy termed Polymer-based Metal-ion Affinity Capture (PolyMAC) for the isolation of phosphopeptides with exceptionally high reproducibility, selectivity, and sensitivity.

PolyMAC1

One-Step Magnetic PolyMAC Phosphopeptide Enrichment

intrument1

PolyMac-Ti with magnetic capture beads

from

$177

The in-solution binding of phosphopeptides to PolyMAC and the covalent capture onto solid-phase beads all occur in a single step. At this point, we offer capture based on magnetic beads only.

All kits include PolyMAC-Ti with magnetic capture beads, loading buffer, two washing buffers and elution buffer.

A magnetic separator rack is not included.

Order now!

One-Step Magnetic PolyMAC
Phosphopeptide Enrichment

intrument1

PolyMac-Ti with magnetic capture beads

from

$177

The in-solution binding of phosphopeptides to PolyMAC and the covalent capture onto solid-phase beads all occur in a single step. At this point, we offer capture based on magnetic beads only.

All kits include PolyMAC-Ti with magnetic capture beads, loading buffer, two washing buffers and elution buffer.

A magnetic separator rack is not included.

Order now!

One-Step PolyMAC Advantages:

Higher reproducibility between experiments and labs
Outstanding reproducibility
Single step phosphopeptide and PolyMAC capture
Fast chelation times
Improved phosphopeptide recovery
Exceptional selectivity