Spin-Tip PolyMAC for enrichment of phosphopeptides
prior to mass spectrometry analysis
PolyMAC is based on a metal-ion functionalized soluble nanopolymer to chelate phosphopeptides in a homogeneous aqueous environment. Compared to current strategies based on solid phase micro- and nano-particles, PolyMAC demonstrates outstanding reproducibility, exceptional selectivity, fast chelation times, and high phosphopeptide recovery from complex mixtures.
Due to low stoichiometry of phosphorylation, phosphopeptide enrichment is a critical step for successful phosphoproteomics experiments. Available here is a novel chemical strategy termed Polymer-based Metal-ion Affinity Capture (PolyMAC) for the isolation of phosphopeptides with exceptionally high reproducibility, selectivity, and sensitivity.
Spin-Tip PolyMAC for enrichment of phosphopeptides prior to mass spectrometry analysis
PolyMAC is based on a metal-ion functionalized soluble nanopolymer to chelate phosphopeptides in a homogeneous aqueous environment. Compared to current strategies based on solid phase micro- and nano-particles, PolyMAC demonstrates outstanding reproducibility, exceptional selectivity, fast chelation times, and high phosphopeptide recovery from complex mixtures.
Due to low stoichiometry of phosphorylation, phosphopeptide enrichment is a critical step for successful phosphoproteomics experiments. Available here is a novel chemical strategy termed Polymer-based Metal-ion Affinity Capture (PolyMAC) for the isolation of phosphopeptides with exceptionally high reproducibility, selectivity, and sensitivity.
Spin-Tip PolyMAC Phosphopeptide Enrichment
Spin-Tip PolyMac-Ti
from
$277
The in-solution binding of phosphopeptides to PolyMAC and the covalent capture onto solid-phase beads all occur in a single step. At this point, we offer capture based on spin-tips only.
All kits include PolyMAC-Ti with capture beads, loading buffer, two washing buffers, elution buffer, fritted spin-tips and centrifuge adapters.
Spin-Tip PolyMAC
Phosphopeptide Enrichment
Spin-Tip PolyMac-Ti
from
$277
The in-solution binding of phosphopeptides to PolyMAC and the covalent capture onto solid-phase beads all occur in a single step. At this point, we offer capture based on magnetic beads only.
All kits include PolyMAC-Ti with capture beads, loading buffer, two washing buffers, elution buffer, fritted spin-tips and centrifuge adapters.
Spin-Tip PolyMAC Advantages:
Spin-Tip PolyMAC Advantages:
Higher reproducibility between experiments and labs
Single step phosphopeptide and PolyMAC capture
Improved phosphopeptide recovery
Exceptional selectivity
Outstanding reproducibility
Fast chelation times
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