Tymora Publications

See our list of selected publications utilizing pIMAGO and PolyMAC.

2017

Bender K, Blackburn R, et.al. (2017). Autophosphorylation-based calcium sensitivity priming of Ca2+/Calmodulin inhibition of Arabidopsis thaliana Ca2+-dependent Protein Kinase 28. J Biol Chem. Epub ahead of print. https://www.ncbi.nlm.nih.gov/pubmed/28154194

Kuzmina A, Krasnopolski S, et.al. (2017). Super elongation complex promotes early HIV transcliption and its function is modulated by P-TEFb. J Transcription. Epub ahead of print. http://www.tandfonline.com/action/showCitFormats?doi=10.1080%2F21541264.2017.1295831

Hsu C-C, Xue L, et.al. (2017). Estimating the efficiency of phosphopeptide identification by tandem mass spectrometry. J Am Soc Mass Spectrom. Epub ahead of print. https://www.ncbi.nlm.nih.gov/pubmed/28283928

Bender K, Blackburn R, et.al. (2017). Autophosphorylation-based calcium sensitivity priming of Ca2+/Calmodulin inhibition of Arabidopsis thaliana Ca2+-dependent Protein Kinase 28. J Biol Chem. Epub ahead of print.

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Kuzmina A, Krasnopolski S, et.al. (2017). Super elongation complex promotes early HIV transcliption and its function is modulated by P-TEFb. J Transcription. Epub ahead of print.

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Hsu C-C, Xue L, et.al. (2017). Estimating the efficiency of phosphopeptide identification by tandem mass spectrometry. J Am Soc Mass Spectrom. Epub ahead of print.

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2016

Li L, Kim P, et.al. (2016). Activation dependent destruction of a co-receptor by a pseudomonas syringae effector dampens plant immunity. Cell Host Microbe. 20(4): 504-14. https://www.ncbi.nlm.nih.gov/pubmed/27736646

Zhao H, Pflug B, et.al. (2016). Pyruvate dehydrogenase alpha 1 as a target of omega-3 polyunsaturated fatty acids in human prostate cancer through a global phosphoproteomic analysis. Proteomics. 16(17): 2419-31.  https://www.ncbi.nlm.nih.gov/pubmed/27357730

Chaput D, PKirouac L, et.al. (2016). Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology. Oncotarget. 7(8): 8481-97.  https://www.ncbi.nlm.nih.gov/pubmed/26885753

Gao X, Jin Q, et.al. (2016). FgPrp4 kinase is important for spliceosome B-complex activation and splicing efficiency in Fusarium graminearum. PLoS Genet. 12(4): e1005973.  https://www.ncbi.nlm.nih.gov/pubmed/27058959

Sroga GE, Vashishth D. (2016). A strategy to quantitate global phosphorylation of bone matrix proteins. Anal Biochem. 499:85-89. http://www.ncbi.nlm.nih.gov/pubmed/26851341

Modak S, Kumar V. (2016). Influence of phosphorylation on the foamability and stability of bovine serum albumin and citrus peel pectin mixed foams. J Disp Sci Technology. 38:1266-1275.  http://www.tandfonline.com/doi/full/10.1080/01932691.2016.1234382?scroll=top&needAccess=true

Batalha I, Roque A. (2016). Phosphopeptide enrichment using various magnetic nanocomposits: an overview. Phosphoproteomics. Methods in Molecular Biology. 1355:193-209. https://www.ncbi.nlm.nih.gov/pubmed/26584927

Xue L, Arrington J, et.al. (2016). Identification of direct kinase substrates via kinase assay-linked phosphoproteomics. Methods Mol Biol. 1355: 263-73. https://www.ncbi.nlm.nih.gov/pubmed/26584932

Iliuk A, Li L, et.al. (2016). Multiplexed imaging of protein phosphorylation on membranes based on Ti(IV) functionalized nanopolymers. Chembiochem. 17(10):900-03. http://www.ncbi.nlm.nih.gov/pubmed/27037847

Niimori Kita K, Nakamura F, et.al. (2016). Nuclear phosphoproteomics features the novel smoking markers in mouse lung tissue following subacute phase exposure to tobacco smoke. J Bioanal Biomed. 8: 09.  DOI: 10.4172/1948-593X.1000146

Pelech S, Yue L. (2016). Profiling signaling protein expression, modifications and interactions with multi-dimensional antibody microarrays. FASEB J. http://www.fasebj.org/content/30/1_Supplement/lb190.short

Li L, Kim P, et.al. (2016). Activation dependent destruction of a co-receptor by a pseudomonas syringae effector dampens plant immunity. Cell Host Microbe. 20(4): 504-14.

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Zhao H, Pflug B, et.al. (2016). Pyruvate dehydrogenase alpha 1 as a target of omega-3 polyunsaturated fatty acids in human prostate cancer through a global phosphoproteomic analysis. Proteomics. 16(17): 2419-31.

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Chaput D, PKirouac L, et.al. (2016). Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology. Oncotarget. 7(8): 8481-97.

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Gao X, Jin Q, et.al. (2016). FgPrp4 kinase is important for spliceosome B-complex activation and splicing efficiency in Fusarium graminearum. PLoS Genet. 12(4): e1005973.

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Sroga GE, Vashishth D. (2016). A strategy to quantitate global phosphorylation of bone matrix proteins. Anal Biochem. 499:85-89.

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Modak S, Kumar V. (2016). Influence of phosphorylation on the foamability and stability of bovine serum albumin and citrus peel pectin mixed foams. J Disp Sci Technology. 38:1266-1275.

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Batalha I, Roque A. (2016). Phosphopeptide enrichment using various magnetic nanocomposits: an overview. Phosphoproteomics. Methods in Molecular Biology. 1355:193-209.

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Xue L, Arrington J, et.al. (2016). Identification of direct kinase substrates via kinase assay-linked phosphoproteomics. Methods Mol Biol. 1355: 263-73.

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Iliuk A, Li L, et.al. (2016). Multiplexed imaging of protein phosphorylation on membranes based on Ti(IV) functionalized nanopolymers. Chembiochem. 17(10):900-03.

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Niimori Kita K, Nakamura F, et.al. (2016). Nuclear phosphoproteomics features the novel smoking markers in mouse lung tissue following subacute phase exposure to tobacco smoke. J Bioanal Biomed. 8: 09.

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Pelech S, Yue L. (2016). Profiling signaling protein expression, modifications and interactions with multi-dimensional antibody microarrays. FASEB J.

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2015

Li M, Yin X, et.al. (2015). Proteomic analysis of phosphoproteins in the rice nucleus during the early stage of seed germination. Journal of Proteome Research. 14(17): 2884-96.  https://www.ncbi.nlm.nih.gov/pubmed/26035336

Muschter S, Berthold T, et.al. (2015). Mass spectrometric phosphoproteome analysis of small-sized samples of human neutrophils. Clinica Chimica Acta. 451:199-207.  https://www.ncbi.nlm.nih.gov/pubmed/26434552

Gendrin C, Lembo A, Whidbey C, Burnside K, Berry J, Ngo L, Banerjee A, Xue L, Arrington J, Doran KS, Tao WA, Rajagopal L. (2015). The sensor histidine kinase RgfC affects group B streptococcal virulence factor expression independent of its response regulator RgfA. Infect Immun. 2015 Mar;83(3):1078-88. http://www.ncbi.nlm.nih.gov/pubmed/25561709

Iliuk A, Jayasundera K, Wang WH, Schluttenhofer R, Geahlen RL, Tao WA. (2015). In-Depth Analyses of B Cell Signaling Through Tandem Mass Spectrometry of Phosphopeptides Enriched by PolyMAC. Int J Mass Spectrom. 2015 Feb 1;377:744-753. http://www.ncbi.nlm.nih.gov/pubmed/25954137

Johnson H. (2015). Uncovering dynamic phosphorylation signaling using mass spectrometry. Int. J. Mass Spectrometry. 391:123-138. http://www.sciencedirect.com/science/article/pii/S1387380615002511

Pan L, Wang L, Hsu CC, Zhang J, Iliuk A, Tao WA. (2015). Sensitive measurement of total protein phosphorylation level in complex protein samples. Analyst. 2015 May 21;140(10):3390-6. http://www.ncbi.nlm.nih.gov/pubmed/25857711

Li M, Yin X, et.al. (2015). Proteomic analysis of phosphoproteins in the rice nucleus during the early stage of seed germination. Journal of Proteome Research. 14(17): 2884-96.

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Muschter S, Berthold T, et.al. (2015). Mass spectrometric phosphoproteome analysis of small-sized samples of human neutrophils. Clinica Chimica Acta. S0009-8981(15)00439-8. 

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Gendrin C, Lembo A, Whidbey C, Burnside K, Berry J, Ngo L, Banerjee A, Xue L, Arrington J, Doran KS, Tao WA, Rajagopal L. (2015). The sensor histidine kinase RgfC affects group B streptococcal virulence factor expression independent of its response regulator RgfA. Infect Immun. 2015 Mar;83(3):1078-88.

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Iliuk A, Jayasundera K, Wang WH, Schluttenhofer R, Geahlen RL, Tao WA. (2015). In-Depth Analyses of B Cell Signaling Through Tandem Mass Spectrometry of Phosphopeptides Enriched by PolyMAC. Int J Mass Spectrom. 2015 Feb 1;377:744-753.

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Johnson H. (2015). Uncovering dynamic phosphorylation signaling using mass spectrometry. Int. J. Mass Spectrometry. 391:123-138.

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Pan L, Wang L, Hsu CC, Zhang J, Iliuk A, Tao WA. (2015). Sensitive measurement of total protein phosphorylation level in complex protein samples. Analyst. 2015 May 21;140(10):3390-6.

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2014

Yin X, Sakata K, et.al. (2014). Phosphoproteomics reveals the effect of ethylene in soybean root under flooding stress. Journal of Proteome Research. 2014 13(12):5618-34. https://www.ncbi.nlm.nih.gov/pubmed/25316100

Han C, Yang P et.al. (2014). Quantitative proteomics reveals the role of protein phosphorylation in rice embryos during early stages of germination. Journal of Proteome Research. 2014 13(3):1766-82. http://pubs.acs.org/doi/abs/10.1021/pr401295c

Yang C, Zhong X, Li L. (2014). Recent advances in enrichment and separation strategies for mass spectrometry-based phosphoproteomics. Electrophoresis. 2014 Dec;35(24):3418-29. http://www.ncbi.nlm.nih.gov/pubmed/24687451

X Liu, Y Li, X Xu, P Li, Z Nie, Y Huang, S Yao. (2014). Nanomaterial based tools for protein kinase bioanalysis. TrAC Trends in Analytical Chemistry. 58:40-53. http://www.sciencedirect.com/science/article/pii/S0165993614000533

Arrington JV, Xue L, Tao WA. (2014). Quantitation of the phosphoproteome using the library-assisted extracted ion chromatogram (LAXIC) strategy. Methods Mol Biol. 2014;1156:407-16. http://www.ncbi.nlm.nih.gov/pubmed/24792004

Xue L, Wang P, Cao P, Zhu JK, Tao WA. (2014). Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics. Mol Cell Proteomics. 2014 Nov;13(11):3199-210. http://www.ncbi.nlm.nih.gov/pubmed/25022875

Jayasundera KB, Iliuk AB, Nguyen A, Higgins R, Geahlen RL, Tao WA. (2014). Global phosphoproteomics of activated B cells using complementary metal ion functionalized soluble nanopolymers. Anal Chem. 2014 Jul 1;86(13):6363-71. http://www.ncbi.nlm.nih.gov/pubmed/24905233

Searleman AC, Iliuk AB, Collier TS, Chodosh LA, Tao WA, Bose R. (2014). Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer. Electrophoresis. 2014 Dec;35(24):3463-9. http://www.ncbi.nlm.nih.gov/pubmed/24723360

Yin X, Sakata K, et.al. (2014). Phosphoproteomics reveals the effect of ethylene in soybean root under flooding stress. Journal of Proteome Research. 2014 13(12):5618-34.

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Han C, Yang P et.al. (2014). Quantitative proteomics reveals the role of protein phosphorylation in rice embryos during early stages of germination. Journal of Proteome Research. 2014 13(3):1766-82.

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Yang C, Zhong X, Li L. (2014). Recent advances in enrichment and separation strategies for mass spectrometry-based phosphoproteomics. Electrophoresis. 2014 Dec;35(24):3418-29.

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X Liu, Y Li, X Xu, P Li, Z Nie, Y Huang, S Yao. (2014). Nanomaterial based tools for protein kinase bioanalysis. TrAC Trends in Analytical Chemistry. 58:40-53.

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Arrington JV, Xue L, Tao WA. (2014). Quantitation of the phosphoproteome using the library-assisted extracted ion chromatogram (LAXIC) strategy. Methods Mol Biol. 2014;1156:407-16.

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Xue L, Wang P, Cao P, Zhu JK, Tao WA. (2014). Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics. Mol Cell Proteomics. 2014 Nov;13(11):3199-210.

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Jayasundera KB, Iliuk AB, Nguyen A, Higgins R, Geahlen RL, Tao WA. (2014). Global phosphoproteomics of activated B cells using complementary metal ion functionalized soluble nanopolymers. Anal Chem. 2014 Jul 1;86(13):6363-71.

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Searleman AC, Iliuk AB, Collier TS, Chodosh LA, Tao WA, Bose R. (2014). Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer. Electrophoresis. 2014 Dec;35(24):3463-9.

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2013

Walls C., Iliuk A., Bai Y., Wang M., Tao WA, Zhang ZY. (2013). Phosphatase of regenerating liver 3 (PRL3) provokes a tyrosine phosphoproteome to drive prometastatic signal transduction. Mol. Cell. Proteomics. 12(12): 3759-77, http://www.ncbi.nlm.nih.gov/pubmed/24030100

Wang P, Xue L, Batelli G, Lee S, Hou YJ, Van Oosten MJ, Zhang H, Tao WA, Zhu JK. (2013). Quantitative phosphoproteomics identifies SnRK2 protein kinase substrates and reveals the effectors of abscisic acid action. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11205-10. http://www.ncbi.nlm.nih.gov/pubmed/23776212

Radu M., Rawat S., Beeser A., Iliuk A., Tao WA., Chernoff J. (2013). ArhGAP15, a Rac-specific GTPase activating protein, plays a dual role in inhibiting small GTPase signaling. Journal of Biological Chemistry. 288(29): 21117-25, http://www.ncbi.nlm.nih.gov/pubmed/23760270

Yu S., Huang H., Iliuk A., Wang W-H., Tao WA., Post C., Geahlen R. (2013). Syk Inhibits the Activity of Protein Kinase A by Phosphorylating Tyrosine 330 of the Catalytic Subunit. Journal of Biological Chemistry. 288(15): 10870-10881, http://www.ncbi.nlm.nih.gov/pubmed/23447535

Xue L, Wang P, Wang L, Renzi E, Radivojac P, Tang H, Arnold R, Zhu JK, Tao WA. (2013). Quantitative measurement of phosphoproteome response to osmotic stress in arabidopsis based on Library-Assisted eXtracted Ion Chromatogram (LAXIC). Mol Cell Proteomics. 2013 Aug;12(8):2354-69. http://www.ncbi.nlm.nih.gov/pubmed/23660473

Walls C., Iliuk A., Bai Y., Wang M., Tao WA, Zhang ZY. (2013). Phosphatase of regenerating liver 3 (PRL3) provokes a tyrosine phosphoproteome to drive prometastatic signal transduction. Mol. Cell. Proteomics. 12(12): 3759-77,

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Wang P, Xue L, Batelli G, Lee S, Hou YJ, Van Oosten MJ, Zhang H, Tao WA, Zhu JK. (2013). Quantitative phosphoproteomics identifies SnRK2 protein kinase substrates and reveals the effectors of abscisic acid action. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11205-10.

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Radu M., Rawat S., Beeser A., Iliuk A., Tao WA., Chernoff J. (2013). ArhGAP15, a Rac-specific GTPase activating protein, plays a dual role in inhibiting small GTPase signaling. Journal of Biological Chemistry. 288(29): 21117-25,

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Yu S., Huang H., Iliuk A., Wang W-H., Tao WA., Post C., Geahlen R. (2013). Syk Inhibits the Activity of Protein Kinase A by Phosphorylating Tyrosine 330 of the Catalytic Subunit. Journal of Biological Chemistry. 288(15): 10870-10881,

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Xue L, Wang P, Wang L, Renzi E, Radivojac P, Tang H, Arnold R, Zhu JK, Tao WA. (2013). Quantitative measurement of phosphoproteome response to osmotic stress in arabidopsis based on Library-Assisted eXtracted Ion Chromatogram (LAXIC). Mol Cell Proteomics. 2013 Aug;12(8):2354-69.

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2012

Chu H et.al. (2012). Identification of cytoskeletal elements enclosing the ATP pools that fuel human red blood cell membrane cation pumps. PNAS. 109(31): 12794-99.  https://www.ncbi.nlm.nih.gov/pubmed/22745158

Pan L, Iliuk A, Yu S, Geahlen RL, Tao WA. (2012). Multiplexed quantitation of protein expression and phosphorylation based on functionalized soluble nanopolymers. J Am Chem Soc. 134(44): 18201-4, http://www.ncbi.nlm.nih.gov/pubmed/23088311   Original pIMAGO-Fluor detection on microplate publication.

Iliuk A, Liu XS, Xue L, Liu X, Tao WA. (2012). Chemical visualization of phosphoproteomes on membrane. Mol. Cell. Proteomics. 11(9): 629-39, http://www.ncbi.nlm.nih.gov/pubmed/22593177   Original pIMAGO-biotin detection on Western Blot publication.

Chu H et.al. (2012). Identification of cytoskeletal elements enclosing the ATP pools that fuel human red blood cell membrane cation pumps. PNAS. 109(31): 12794-99.

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Pan L, Iliuk A, Yu S, Geahlen RL, Tao WA. (2012). Multiplexed quantitation of protein expression and phosphorylation based on functionalized soluble nanopolymers. J Am Chem Soc. 134(44): 18201-4,

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Iliuk A, Liu XS, Xue L, Liu X, Tao WA. (2012). Chemical visualization of phosphoproteomes on membrane. Mol. Cell. Proteomics. 11(9): 629-39,

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2011

Xue L, Wang WH, Iliuk A, Hu L, Galan JA, Yu S, Hans M, Geahlen RL, Tao WA (2012). Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates. PNAS. 109(15): 5615-20, http://www.ncbi.nlm.nih.gov/pubmed/22451900

Iliuk A, Jayasundera K, Schluttenhofer R, Tao WA (2011). Functional soluble nanopolymers for phosphoproteome analysis. Methods Mol. Biol. 790: 277-85, http://www.ncbi.nlm.nih.gov/pubmed/21948422

Iliuk A, Martinez J, Hall MC, Tao WA (2011). Phosphorylation assay based on functionalized soluble nanopolymer. Anal. Chem. 83(7): 2767-74, http://www.ncbi.nlm.nih.gov/pubmed/21395237  Original pIMAGO-biotin detection on microplate publication.

Xue L, Wang WH, Iliuk A, Hu L, Galan JA, Yu S, Hans M, Geahlen RL, Tao WA (2012). Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates. PNAS. 109(15): 5615-20,

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Iliuk A, Jayasundera K, Schluttenhofer R, Tao WA (2011). Functional soluble nanopolymers for phosphoproteome analysis. Methods Mol. Biol. 790: 277-85,

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Iliuk A, Martinez J, Hall MC, Tao WA (2011). Phosphorylation assay based on functionalized soluble nanopolymer. Anal. Chem. 83(7): 2767-74,

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2010

Iliuk AB, Martin VA, Alicie BM, Geahlen RL and Tao WA (2010). In-depth analyses of kinase-dependent tyrosine phosphoproteomes based on metal ion functionalized soluble nanopolymers. Mol. Cell. Proteomics. 9: 2162-2172, http://www.ncbi.nlm.nih.gov/pubmed/20562096  Original PolyMAC-Ti publication.