Cell Lysate Proteomics

We have developed and optimized highly effective and reproducible methods for cell lysate analysis, including efficient protein extraction (containing membrane proteins), two-step sequential digestion, and phosphopeptide enrichment using our soluble PolyMAC reagent.

Why choose Tymora Analytical cell lysate proteomics?

We now offer a unique ability for low abundant protein analysis, glycoprotein analysis in cell lysates, post-translational modification analysis in frozen cells, cell phosphoproteomics analysis, and others from frozen cells or cell lysate samples.

Our goal is to help scientists use cell lysate proteomics analysis to discover new biomarkers and drug targets for earlier, more effective diagnoses and treatments. 

Our LC-MS/MS analysis-based services include:

  • Global Proteome Analysis
  • Phosphoproteome Analysis
  • Glycoprotein Analysis in Cell Lysates
  • LC-MS/MS Analysis of Low Abundant Proteins
  • Other Post-Translational Modification Analysis in Frozen Cells

We can also provide label-free quantitation for comparative analysis.

Most samples are analyzed within two to three weeks from receipt.

As an example, using our novel approach of protein extraction, two-step sequential digestion, and our soluble PolyMAC-based phosphopeptide enrichment, we were able to identify ~8,800 unique phosphopeptides from a single 30ug B cell lysate sample.

Contact us for more information.

Contact Tymora Analytical for more information about our cell lysate proteomics/PTM services, to create a custom work plan based on your needs, and to get a quote. Business partnership opportunities are also available.
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